Bibliographie

Publications les plus représentatives

BAULIEU, E.-E., LASNITZKI, I., ROBEL, P.

Metabolism of testosterone and action of metabolites on prostate glands grown in organ culture
Nature (1968) 219, 1155-1156


BAULIEU, E.-E., GODEAU, J.F., SCHRODERET, M., SCHORDERET-SLATKINE, S.

Steroid induced meiotic division in Xenopus laevis oocytes: surfaces and calcium.
Nature (1978) 275, 593-598


FINIDORI-LEPICARD, J., SCHORDERET-SLATKINE, S., HANOUNE, J., BAULIEU, E.-E.

Steroid hormone as regulatory agent of adenylate cyclase. Inhibition by progesterone of the membrane bound enzyme in Xenopus laevis oocytes
Nature (1981) 292, 255-256


CORPECHOT, C., ROBEL, P., AXELSON, M., SJÖVALL, J., BAULIEU, E.-E.

Characterization and measurement of dehydroepiandrosterone sulfate in the rat brain
Proc. Natl. Acad. Sci., USA (1981) 78, 4704-4707


JOAB, I., RADANYI, C., RENOIR, J.M., BUCHOU, T., CATELLI, M.G., BINART, N., MESTER, J., BAULIEU; E.-E.

Immunological evidence for a common non hormone-binding component in " non-transformed " chick oviduct receptors of four steroid hormones
Nature (1984) 308, 850-853


BAULIEU, E.-E.

Contragestion and other applications of RU486, an antiprogesterone at the receptor
Science (1989) 245, 1351-1357


LEBEAU, M.C., MASSOL, N., HERICK, J., FABER, L.E., RENOIR, J.M, RADANYI, C., BAULIEU, E.-E.

P59, an hsp90 binding protein; cloning and sequencing of its cDNA. Preparation of a peptide-directed polyclonal antibody.
J. Biol. Chem. (1992) 267, 4281-4284


PEYRON, R., AUBENY, E., TARGOSZ, V., SILVESTRE, L., RENAULT, M., ELKIK, F., LECLERC, P., ULMANN, A., BAULIEU, E.-E.

Early termination of pregnancy with mifepristone (RU486) and the orally active prostaglandin Misoprostol.
New Engl. J. Med.(1993) 328, 1509-1513


RADANYI, C., CHAMBRAUD, B., BAULIEU, E.-E.

The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetrotricopeptide repeat domain.
Proc. Natl. Acad. Sci. USA (1994) 91, 11197-11201


KOENIG, H.L., SCHUMACHER, M., FERZAZ, B., DO THI, A.N., RESSOUCHES, A., GUENNOUN, R., JUNG-TESTAS, I., ROBEL, P., AKWA, Y., BAULIEU, E.-E.

Progesterone synthesis and myelin formation by Schwann cells.
Science (1995) 268, 1500-1503


BERR, C., LAFONT, S., DEBUIRE, B., DARTIGUES, J.F., BAULIEU, E.-E.

Relationships of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mortality. A French community-based study
Proc. Natl. Acad. Sci. USA (1996) 93, 13410-13415


CHAMBRAUD, B., RADANYI, C., CAMONIS, H., RAJKOWSKI, K., SCHUMACHER, M., BAULIEU, E.-E.

Immunophilins, Refsum disease and Lupus nephritis. The peroxisomal enzyme phytanoyl-coa a-hydroxylase is a new FKBP-associated-protein.
Proc. Natl. Acad. Sci. USA (1999) 96, 2104-2109


SCHUMACHER, M., AKWA, Y., GUENNOUN, R., ROBERT, F., LABOMBARDA, F., DESARNAUD, F., ROBEL, P., DE NICOLA, A.F., BAULIEU, E.-E.

Steroid synthesis and metabolism in the nervous system : Trophic and protective effects.
Journal of Neurocytology (2000) 29, 307-326


AKWA Y., LADURELLE N., COVEY D.F., BAULIEU E.-E.

The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart : distinct mechanisms ?
Proc Natl Acad Sci USA (2001) 98, 14033-14037


MAZAT L., LAFONT S., BERR C., DEBUIRE B, TESSIER J.F., DARTIGUES J.F., BAULIEU E.-E.

Prospective measurements of dehydroepiandrosterone sulfate in a cohort of elderly subjects : Relationship to gender, subjective health, smoking habits and 10-year mortality
Proc. Natl. Acad. Sci. USA (2001) 98, 8145-8150



Principaux ouvrages

BAULIEU E.-E., KELLY P. A.

Hormones : from molecules to diseases
Ed. Hermann (1990) 697 p.


BAULIEU E.-E.

Génération pilule
Ed. Odile Jacob (1990) 314 p.


BAULIEU E.-E.

The abortion Pill
Ed. Simon & Scuster (1991) et Century (1992)


BAULIEU E.-E., ROBEL P., SCHUMACHER M.

Neurosteroids : a new regulatory function in the nervous system
Ed. Humana Press (1999) 378 p.


BAULIEU É.-É., HÉRITIER F., LÉRIDON H.

Contraception, contrainte ou liberté ?
Ed. Odile Jacob (1999) 305 p.


BAULIEU E.-E.

Longévité, tous centenaires ?
Ed. Platyplus Press (2003) 125 p.

PLASSART-SCHIESS E. and BAULIEU E.E.

"New" modes of action of steroids : the case of neurosteroids In : Menopause, hormones and cancer, Proceedings of the 2nd International Symposium of the Portuguese Menopause Society, Neves-e-Castro M. and Wren
B.G. eds (Parthenon Publishing, London), chap. 1, 1-8, 2002.


BELANOFF J.K., ROTHSCHILD A.J., CASSIDY F., DEBATTISTA C., BAULIEU E.E., SCHOLD C., and SCHATZBERG A.F.

An open label trial of C-1073 (Mifepristone) for psychotic major depression
Biol Psychiatry, 52, 386-392, 2002.


WEILL-ENGERER S., DAVID J.P., SAZDOVITCH V., LIERE P., EYCHENNE B., PIANOS A., SCHUMACHER M., DELACOURTE A., BAULIEU E.E., and AKWA Y.

Neurosteroid quantification in human brain regions : comparison between Alzheimer's and nondemented patients.
J. Clin. Endocrinol. Metab., 87, 5138-5143, 2002


BAULIEU E.E.

Andropause at the beginning of the new century : a few remarks on hormones and aging of men. In : Women's Health and Menopause. New strategies-improved quality of life.
R.A. Lobo, P.G. Crosignani, R. Paoletti and F. Bruschi, eds (Fondazione Giovanni Lorenzini Milan, Kluwer Academic Publishers), 17, 7-21, 2002.


BENMESSAHEL Y., GUENNOUN R., CADEPOND F., BAULIEU E.E., SCHUMACHER M., GROYER G.

Expression of steroidogenic acute regulatory protein in cultured Schwann cells and its regulation by cAMP
Ann N Y Acad Sci, 973, 83-87, 2002.


CADEPOND F., MASSAAD C., TROUSSON A., GRENIER J., GROYER G., BAULIEU E.E., SCHUMACHER M.

Steroid receptors in various glial cell lines expression and functional studies.
Ann N Y Acad Sci, 973, 484-487, 2002.


Baulieu E.E.

Androgens and aging men
Molecular and Cellular Endocrinology 198:41-49, 2002.


Weill-Engerer S., David J.P., Sazdovitch V., Liere P., Schumacher M., Delacourte A., Baulieu E.E., Akwa Y.

In vitro metabolism of dehydroepiandrosterone (DHEA) to 7a-hydroxy-DHEA and D5-androstene-3b-17b-diol in specific regions of the aging brain from Alzheimer's and non-demented patients
Brain Research 969:117-125, 2003.


Krummrei U., Baulieu E.E. and Chambraud B.

The FKBP-associated protein FAP48 is an antioproliferative molecule and a player in T cell activation that increases IL2 synthesis
Proc Natl Acad Sci USA 100:2444-2449, 2003.


Percheron G., Hogrel J.Y., Denot-Ledunois S., Fayet G., Forette F., Baulieu E.E., Fardeau M., Marini J.F.

Effet of 1-year oral administration of Dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area
Arch Intern Med. 163:720-727, 2003.


Ghoumari A.M., Dusart I., El-Etr M., Tronche F., Sotelo C., Schumacher M., and Baulieu E.E.

Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum
Proc Natl Acad Sci USA 100:7953-7958, 2003.


Ibanez C., Guennoun R., Liere P., Eychenne B., Pianos A., El-Etr M., Baulieu E.E., and Schumacher M.

Developmental expression of genes involved in neurosteroidogenesis : 3b-hydroxysteroid dehydrogenase/D5-D4 isomerase in the rat brain
Endocrinology 144:2902-2911, 2003.


Bonnet S., Dumas de La Roque E., Bégueret H., Marthan R., Fayon M., Dos Santos P., Savineau J.P., and Baulieu E.E.

Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension
Proc Natl Acad Sci USA 100:9488-9493, 2003.


Ghoumari A.M., Ibanez C., El-Etr M., Leclerc P., Eychenne B., O'Malley B.W., Baulieu E.E. and Schumacher M.

Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum
J. Neurochem 86:848-859, 2003.


Akwa Y. and Baulieu E.E.

On the neurosteroid mechanisms of action and their clinical potentials. In : Neurosteroid effect in the central nervous system : the role of the GABAA
receptor, Smith S. ed. (CRC Press LLC, Boca Raton, USA), 17:359-372, 2003.


Ibanez C., Shields S.A., El-Etr M., Leonelli E., Magnaghi V., Li W.W., Sim F.J., Baulieu E.E., Melcangi R., Schumacher M., Franklin R.J.M.

Steroids and the reversal of age-associated changes in myelination and remyelination.
Progress in Neurobiology 71:49-56, 2003.


Schumacher M., Weill-Engerer S., Liere P., Robert F., Franklin R.J.M., Garcia-Segura L.M., Lambert J.J., Mayo W., Melcangi R.C., Parducz A., Suter U., Carelli C., Baulieu E.E., Akwa Y.

Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.
Progress in Neurobiology 71:3-29, 2003.


Massol N., Lebeau M.C., Schumacher M., and Baulieu E.E.

Promoter activity and gene structure of rabbit FKBP52
DNA and Cell Biology 22:505-511, 2003.


Ibanez C., Shields S.A., El-Etr M., Baulieu E.E., Schumacher M. and Franklin R.J.M.

Systemic progesterone administration results in a partial reversal of the age-associated decline in CNS remyelination following toxin-induced demyelination in male rats
Neuropathology and Applied Neurobiology 30:80-89, 2004


Ghoumari A.M., Baulieu E.E.

L'antistéroïde RU486 peut aussi protéger contre la mort neuronale
La Lettre du Neurologue VIII:75-76, mars 2004


Guennoun R., De Nicola A.F., Schumacher M. and Baulieu E.E.

Progesterone in the nervous system : an old player in new roles
In : Hormone replacement therapy and the brain. A.R. Genazzani ed. (International Menopause Society, The Parthenon Publishing Group), 57-71, 2004.


Schumacher M., Guennoun R., Robert F., Carelli C., Gago N., Ghoumari A., Gonzalez Deniselle M.C., Gonzales S.L., Ibanez C., Labombarda F., Coirini H., Baulieu E.E., De Nicola A.F.

Local synthesis and dual actions of progesterone in the nervous system : neuroprotection and myelination
Growth Hormone & IGF Research, 14:S18-S33, 2004.


Varet J., Vincent L., Akwa Y., Mirshahi P., Lahary A., Legrand E., Opolon P., Mishal Z., Baulieu E.E., Soria J., Soria C., Li H.

Dose-dependent effect of dehydroepiandrosterone, but not of its sulphate ester, on angiogenesis.
Eur. J. Pharmacol, 502:21-30, 2004.


Liere P., Pianos A., Eychenne B., Cambourg A., Liu S., Griffiths W., Schumacher M., Sjövall J. and Baulieu E.E.

Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain.
J Lipid Res, 45:2287-2302, 2004.


Baulieu E.E., Robel P., Fellous A., Duchossoy Y., Fontaine-Lenoir V., David S.

Treating Alzheimer's disease : new directions in drug discovery/development.
Journal of Molecular Neuroscience, 24:063-066, 2004.


Matsunaga M., Ukena K., Baulieu E.E., and Tsutsui K.

7a-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system.
Proc Natl Acad Sci USA 101:17282-17287, 2004.


Schumacher M., Ghoumari A., Guennoun R., Labombarda F., Gonzalez S.L., Gonzalez Deniselle M.C., Massaad C., Grenier J., Rajkowski K.M., Robert F., Baulieu E.E., and De Nicola A.F.

Progestins and antiprogestins : mechanisms of action, neuroprotection and myelination.
in : Hormones and the Brain.. Kordon et al. eds (Springer-Verlag Berlin, Heidelberg), 111-154, 2005.


Discours les plus représentatifs

BAULIEU E.E.

La recherche fondamentale et le devoir de communiquer
La Lettre de l'Académie des Sciences, 3, Editorial, 2002.


BAULIEU E.E.

Longévité et vieillissement : aspects scientifiques, médicaux et sociaux
La Lettre de l'Académie des Sciences, 3, 3-6, 2002.


Baulieu E.E.

a) La science est progrès - Allocution de prise de fonction du Professeur Etienne-Emile Baulieu, Président de l'Académie des sciences 2003-2004, 14 janvier 2003 [en ligne].
b) Science is Progress Address by Professor Etienne-Emile Baulieu, President of the Academy of Sciences 2003-2004, January 14, 2003 [on line].
Disponibles sur : http://www.academie-sciences.fr


Baulieu E.E.

a) Changements de la science, progrès pour l'homme ? Séance solennelle de rentrée des cinq Académies, 21 octobre 2003 [en ligne].
b) Scientific change, a step forward for mankind ? Official Opening Ceremony, October 21st, 2003 [on line].
Disponibles sur : http://www.academie-sciences.fr


Baulieu E.E.

Longévité et vieillissement : le rôle des hormones (Conférence du 15 mai 2003)
Bulletin de la Société des Amis des Universités de l'Académie de Strasbourg 57:47-58, 2003.


Baulieu E.E.

a) Discours prononcé par E.E. Baulieu le 27 novembre 2003, à l'Hôtel Matignon, lors de la remise de la Légion d'Honneur à sept membres de l'Académie des sciences par Jean-Pierre Raffarin, Premier Ministre [en ligne].
b) Speech by E.E. Baulieu, November 27, 2003, at the Hôtel Matignon at the invitation of Prime Minister Jean-Pierre Raffarin [on line].
Disponibles sur : http://www.academie-sciences.fr


Baulieu E.E., Robel P., Fellous A., Duchossoy Y., Fontaine-Lenoir V. et David S.

Des neurostéroïdes agissent directement au niveau des microtubules. Vers une nouvelle approche de la neuroprotection et du traitement de la maladie d'Alzheimer.
Communication présentée au colloque Nouvelles approches en neurosciences et maladies du système nerveux central, Paris (Académie des sciences), 10-12 mai 2004


Baulieu E.E.

Académie des sciences. Allocution du Président sortant Etienne-Emile Baulieu. Séance publique du 11 janvier 2005 [en ligne].
Allocution disponible sur : http://www.academie-sciences.fr


Baulieu E.E.

Le CIP, originalité d’une démarche, bilan de son fonctionnement 2004, la France et sa recherche.
in : Les Etats Généraux de la Recherche. D. Peschanski ed (Tallandier, Paris) XV:340-342, 2005.


Baulieu E.E., Brézin E.

La grande misère de la recherche en France.
in : le débat. Pierre Nora ed. (Gallimard) 134:92-104, 2005.


Baulieu E.E.

Le plaisir est excellent pour la santé.
in : Passionnément vieux. L. Delwasse, F. Delpech eds (Anne Carrère) 119-128, 2005.


Baulieu E.E.

Hormones, environnement et soi.
Communication présentée le 24 juin 2005 au Colloque : L’identité ? Soi et non soi, Institut de France, Paris.


Baulieu E.E.

La quête de la jouvence.
Sève 13:69-75,2007. Dossier: Le temps et la santé.


Baulieu E.E.

Entretien avec le professeur E.E. Baulieu (propos recueillis en avril 2002 et révisés en octobre 2006).
in : Les Dialogues stratégiques. V. Anger ed (Des Idées & des Hommes, Paris), I 83-187, 2007.